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The world of business has been expanding over the years, and e-commerce is at the cutting edge of technological advancement. With all these strides that online business is taking, curiosity can lead you to ask whether all kinds of products are affected. Of interest in this piece is the purchase of ED drugs; Cialis in particular. Is it possible to purchase it online? And if we can, what then are the rules to follow when buying Cialis online?
Tadalafil improves erection during sex and helps achieve a satisfactory sexual intercourse. Pharmaceutical services have given us an opportunity to buy Cialis online, at different doses. Today, the product is rated highly by consumers as well as retailers who are reaping a fortune from it.
Having a sense of the mechanism of action of Cialis will help us in understanding the complete details of its online market. The drug is phosphodiesterase type 5 (PDE5) inhibitor specific to cyclic guanosine monophosphate (cGMP). It is sold as a pill for treating erectile dysfunction (ED), under the name Cialis. When used to treat pulmonary arterial hypertension it goes by the name Adcirca. From history, the drug was developed by the biotechnology company ICOS, and marketing on a global scale is done by Eli Lilly and ICOS.
The drug is available in the form of tablets available in the following strengths: 2.5 mg, 5 mg, 10 mg, and 20 mg. They are yellow, film-coated and almond-shaped. There is an exception for the treatment of pulmonary arterial hypertension that requires 40 mg (two 20-mg tablets) once daily. In November 2011, the U.S. Food and Drug Administration(FDA) approved Cialis for sale in the United States as the third prescription drug for the treatment of erectile dysfunction. Other drugs that have been used to boost the man’s ability in the game are Viagra and Levitra. Tadalafil can be utilized as a use-when-needed medication or on a daily basis.
Recently tadalafil has also been approved for the treatment of signs and symptoms of benign prostatic hyperplasia (BPH). In cases when a patient is suffering from both prostatic hyperplasia and erectile dysfunction simultaneously, Cialis pills have proven to be highly effective too. The scientific formula for tadalafil is C22H19N3O4, and the molar mass is 389.404 g/mol. The pharmacokinetic profile of Cialis is one of its kind. It has a bioavailability that varies, the protein binding is 94%, metabolism is done by the Cytochrome p450, CYP3A4 in the liver. The biological half-life is estimated at 17.5 hours. It’s excreted with feces and urine, at 60% and 30%.
Different ways have been developed to identify this exclusive drug, especially for men. The CAS number is 171596-29-5, and the ATC code by WHO is G04BE08. Following the approval of Cialis in the 2000s, there have been massive purchases exceeding US$ I billion.
Pros of buying Cialis online
There are days when you decide to visit the doctor, and when you arrive at the clinic, it almost seems as if the whole city got sick. The queue is long and sitting to wait is nothing but a test of your patience. Again passing by the pharmacy after work doesn’t seem to be any better, more so if you want to buy an ED drug. Due to the aforementioned, buying drugs online becomes quite a relief. I bet the most appropriate way to buy Cialis is via the online platforms. Many advantages come with the online purchase. The benefits resulting from buying the it online are varied, and one has to see which attract them most. Men’s health is critical, and their potency is of paramount importance. One thing for sure; buying Cialis online is convenient.
There is assurance of privacy with buying Cialis online. In some places, the very mention of a prescription for erectile dysfunction is almost unfathomable. It is viewed as a sign of weakness and inability, an attitude that could keep many off the purchase. When one buys tadalafil online, they can order at any time of their convenience since the websites run for 24 hours. There is unparalleled privacy as nobody can trace the buyer of the particular product.
There is improved accessibility for the people living in remote areas. There are many people to whom the idea of popping into the pharmacy downstairs is a nightmare. That means that they may have to travel for some miles to make the purchase of the drug they really crave for. However, with the Cialis online platform, they can make orders, and all they have to do is wait for delivery. The cost of a strenuous trip, fuel costs and time expenses are cut down magically, just as it works in the bedtime moment. You have no excuse for missing the bright moments just because your abode is situated far from time.
There is better comparability of prices when buying Cialis online. Different pharmaceutical companies and shops will have different prices for the same commodity. They can compare the prices quoted by different websites. There are 20 mg, 10 mg and even 5 mg tablets and they have different prices. That would mean that one can compare the shipping prices and the actual cost of the drug and make an appropriate decision on where to buy the drug from.
Other benefits include easier access to production information that is in writing. Furthermore, one can contact many practicing pharmacists and doctors online and ask any questions about Cialis.
Cons of buying Cialis online
The risks of buying Cialis online are similarly multiple, and every customer must exercise a standard of caution. Some of the risks may be trivial, but others may be life-threatening and fatal in extreme cases. These risks develop from the fact that the patient deciding to go straight for buying online without consulting the doctor first is never reviewed by the physician to gauge their health condition and the doses required for each.
Most Cialis pills (especially the generic ones) are bought online without prescriptions are the user has to read and gauge the amount reasonable for them. The danger coming with this is that other conditions like renal failure and adequate liver function tests ought to be done before prescription. Such tests are most done in a clinical setup and missing that may cause problems. There are cases when individuals took lower doses than the required amounts and failed to achieve their target during the sexual act. An overdose is even worse since it can lead to excess dilation of the vessels of the penis resulting in their rupture, and in some instances, priapism.
There have been cases of buyers receiving drugs different from those that were ordered. Although most companies are reliable and genuine, there are charlatans looking for quick money. Some drugs are not approved by the FDA, but some pharmacies do sell them. The risk is that some drugs have many adverse effects that can endanger the life of the user.
There is an increased chance of buying counterfeit medicine when purchasing online. It is estimated that a half of the drugs for erectile dysfunction sold online are actually fake. Some may be placebos while others have other active ingredients that are not tadalafil. FDA warns that there are products that do contain particularly dangerous ingredients that could harm the user.
Rules to follow when buying Cialis on the Web
There are a few basic guidelines that we need to consider when we buy Cialis online. This will help escape the pitfalls that are associated with online buying.
Undertake a search on the approximate price of the Cialis drug. Reasonably, the price and quality of a commodity will correspond. If one gets a company that sells the same drug too cheaply, they should be alarmed that it might be a counterfeit drug; though this is not always the case. Conmen take advantage of desperate buyers.
Take a simple investigation of the operation that is selling the drug. It is likely that a company that has been accused of selling fake products offers fake Cialis. If a company has been accused of some dubious ways, it cannot be trusted and will require much time to win back the trust of customers.
Confirm that the vendor selling Cialis online is situated where it claims to. It is easy to tell from websites that the company is from a different state or even country, but it provides different information. The online pharmacy should have a physical address and an operational telephone number. It does no harm to communicate with the customer care in attempts to test the number that has been availed by the seller.
There are government legislations that must be considered. An add-on to support that the drug is FDA-authorized may be necessary for safety. The reality is that not every company that has a website and claims to sell Cialis online is genuine and reliable.
Finally, you need to read the terms and conditions of the company and their delivery policies.
Cialis 5mg (just like 20mg and 10mg) is an ellipsoid tablet, light yellow in color with “C5” imprinted on it. As the name suggests, Cialis 5mg has a tadalafil content of 5 milligrams per tablet. The drug comes in 14-tablet and 28-tablet packages with marketing IDs of EU/1/02/237/007 and EU/1/02/237/008 respectively. It is completely film-coated with opadry II system 32K12891 yellow and contains 121 milligrams of lactose. Cialis 5 mg is an oral drug taken continuously once daily at approximately the same time for up to twenty-six weeks.
It is used in the treatment and management of signs and symptoms of Erectile Dysfunction (ED), symptoms of Benign Prostatic Hyperplasia (B.P.H) or both (if occurring concurrently). In this case, it is basically a maintenance dose. When used as a fix for ED, the person will be ready for sexual activity all day long as long as the moment is right. The dosage can be reduced to 2.5 mg based on the individual’s ability to tolerate the drug’s strength. For Cialis 5mg to work efficiently as a remedy for ED, sexual excitement is an essential recipe in the person’s life.
When used in treating benign prostatic hyperplasia, the starting dose is always 10 milligrams accompanied by finasteride then continued as Cialis 5mg for up to twenty-six weeks. When treating both erectile dysfunction and symptoms of benign prostatic hyperplasia, the dose should be taken once daily at an almost fixed time of day, disregarding sexual activity. It is also given as a starting dose not more than once per day for patients with renal impairment and then increased to a maximum of 10 milligrams per the individual’s progress.
It is commonly taken concurrently with meals, but this is not necessary. The drug works equally well when taken without food. Cialis 5mg is the most common and viable for use as a relief for symptoms of benign prostatic hyperplasia since it permits a continued everyday use. This ensures real-time monitoring, management and change of dosage with a physician’s recommendation should the need arise.
Cialis 10 mg
As with other tablets, Cialis 10mg is a light yellow oval-shaped tablet. It is also completely coated with iron oxide yellow CI77492 yellow with the characters “C10” written on its sides for easy identification and to distinguish it. With the coating, Cialis 10 mg contains 170mg of lactose. It is always used as the start dosage in treating erectile dysfunction on use-as-needed basis (mostly for conditions caused by anxiety and stress) and symptoms of benign prostatic hyperplasia. Adjustments made to dosage, for instance, increasing it to 20 or decreasing it to 5 is purely based on the doctor’s judgment and the user’s consent. Cialis 10mg is produced in packages containing four tablets each and identified universally using the marketing ID of EU/1/02/237/001.
This dosage of Cialis is a use-on-demand only dose and is not always recommended for a prolonged continued use. If Cialis 10 mg is used to relieve erectile dysfunction, it is active for up to 36 hours after the dose is consumed. It should be taken at least 30 minutes before sexual activity to allow for the uptake and maximum assimilation of the drug.
In individuals with renal impairment accompanied by creatinine clearance of between 30 mL/min and 50mL/min, a maximum of it should be taken not more than once in every 48 hours. If the creatinine clearance is below 30ml/min, a maximum of drug should be taken in 72 hours.
In the event of hepatic failure, the dosage should be restricted to not more than Cialis 10mg in 24 hours. It is also the upper dosage limit recommended for any individual taking concomitant inhibitors of CYP3A4 and should be taken not more than once in every 72 hours.
Cialis 20mg is a yellow, 12-millimeter long, almond-shaped tablet that is fully coated with iron oxide yellow CI77492 film and contains 20mg of the active component tadalafil. With the coating intact, it contains 233mg of lactose. To distinguish it “c20” is engraved on its sides.
It comes in four different packages, with 2, 4, 8 and 12 tablets. The assigned marketing IDs are EU/1/02/237/002, EU/1/02/237/003, EU/1/02/237/004, and EU/1/02/237/005 respectively.
Cialis 20mg is the highest dose that is recommended for treating erectile dysfunction. It is a use-when-needed med taken only before anticipated sexual activity. Because of the high tadalafil content, it is mostly not recommended for continuous use as it bears serious side effects.
When taken as needed, Cialis 20mg should be taken at least 30 minutes before sexual activity can begin. Some active ingredients can remain in the body for as long as two days for a person with normal hepatic and renal function, but they could stay longer in patients with renal and liver failure since its metabolites may not be adequately excreted.
In cases when individuals cannot tolerate the 20mg dose, the dosage can be decreased to 10 but raising the dosage beyond this even with high self-efficacy from the individual is highly discouraged and not recommended. It should be mentioned, however, that a 30mg dose is an option in rare situations. Any dose beyond 20 milligrams is strictly under the instructions and close monitoring by a physician.
There are various contraindications and side effects that would call for the cessation of the dose or switch to a less potent Cialis dose. Stopping the medication is an option if one experiences nausea, dizziness, nasal congestion, pain in the eyes, blurred vision, fast heart rate, ringing sounds in the ears, increased sweating, seizures and bleeding in the penis. A decrease in blood pressure is also an indicator for action regarding the medication and the dosage. In most cases, it is advised to stop the treatment for a while.
Cialis is a drug used to treat erectile dysfunction and it can definitely be said out loud that its effects are magical. As the pharmaceutical world goes online, the purchase of tadalafil on the Web has been made ridiculously easy. Just don’t forget to follow the simple rules laid out above in this article and your treatment with drug bought online shouldn’t be any different from what you get with brand-name Cialis from your local brick-and-mortar pharmacy. Enjoy!